X
Pharma Advancement
  • Home
  • Drug Development
    • All
    • Clinical Trials
    • FDA Approvals
    • Research & Development

    New Delivery Path Brings To Light Efficacy of Immunotherapy

    Nasal Spray Shows Its Effect Against New COVID Variants

    Mid-Point Regulatory Science Strategy Study Published By EMA

    AADC Inadequacy To Be Handled By A Novel Gene Therapy

    New Drug Explored For Epilepsy Gets $3M Funding In Australia

    Care Access Research Launches Alliance to Provide Infrastructure for COVID-19 Trials

    Faster Clinical Trial Nods Planned By The UK To Curb Issues

    Pharma Drugs Gain From Tardigrade Proteins, Says Research

    Pharma Drugs Gain From Tardigrade Proteins, Says Research

    U.S. FDA Approves DARZALEX Split-Dosing Regimen

    EMA Keeping A Close Watch On Critical Medicine Shortages

    Pathways Laid Down By The CMS For Drug Price Negotiations

    Pathways Laid Down By The CMS For Drug Price Negotiations

  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us
No Result
View All Result
  • Home
  • Drug Development
    • All
    • Clinical Trials
    • FDA Approvals
    • Research & Development

    New Delivery Path Brings To Light Efficacy of Immunotherapy

    Nasal Spray Shows Its Effect Against New COVID Variants

    Mid-Point Regulatory Science Strategy Study Published By EMA

    AADC Inadequacy To Be Handled By A Novel Gene Therapy

    New Drug Explored For Epilepsy Gets $3M Funding In Australia

    Care Access Research Launches Alliance to Provide Infrastructure for COVID-19 Trials

    Faster Clinical Trial Nods Planned By The UK To Curb Issues

    Pharma Drugs Gain From Tardigrade Proteins, Says Research

    Pharma Drugs Gain From Tardigrade Proteins, Says Research

    U.S. FDA Approves DARZALEX Split-Dosing Regimen

    EMA Keeping A Close Watch On Critical Medicine Shortages

    Pathways Laid Down By The CMS For Drug Price Negotiations

    Pathways Laid Down By The CMS For Drug Price Negotiations

  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us
No Result
View All Result
Pharma Advancement
No Result
View All Result
Home Europe

Roche Pharmaceutical Manufacturing Plant

Yuvraj_pawp by Yuvraj_pawp
8th August 2014
in Europe, Projects

Roche Mustahzarlari has completed the construction of their pharmaceutical facility at Gebze, close to Istanbul, Turkey. The new drugs manufacturing facility will make solid dosage forms, including packaging of the finished products. The facility, which has a floor space of 18,000m², includes new quality control laboratories, warehousing, offices and administration buildings.

The facility is Roche’s second-largest solid forms production plant. The project was valued at approximately $60 million. Work on the new plant began in July 2000 and, now completed, it is scheduled to begin production on 20 October 2003. The plant will produce 61 million packages of medicine in the first year. This will meet fully the domestic market demand for capsules and tablets and also allow some export to Eastern Europe.

PHARMACEUTICAL PLANT CONSTRUCTION

The Roche subsidiary decided to award the lead contract for the pharmaceutical manufacturing plant to Foster Wheeler Italiana SpA. The contract was for the provision of engineering, procurement and construction management. Foster Wheeler managed the main part of the work from its Italian centre in Milan.

TRANSITION PHASE

The plant is scheduled to enter production in October 2003. However, for the first few months this will only involve packaging. The older and smaller Roche plant at Levent, Turkey will continue production during a transition phase to the new plant.

Rockwell Automation are implementing a logistics software and production package – Propack Data PMX MESTM – to assist Roche in the transport of products between the plants, dispensing and packaging the products and their subsequent distribution from a fully automated warehousing facility to customers in Eastern Europe.

HARD GELATINE CAPSULES AND SOFT ELASTIC CAPSULES

The plant will make capsules of solid dosage forms, in which one or more medicinal and inert ingredients are enclosed in a small shell or container usually made of gelatine. The plant will make both hard gelatine capsules and soft elastic capsules.

Hard gelatine capsules are made out of a larger portion (the body) and a smaller section (the cap). Both commercially and extemporaneously, the method of filling requires that the amount of powder containing the given dose must be matched with the volume contained in the body of the capsule. Conventional capsules are oblong with curved ends. They are usually clear but can be coloured during manufacture by incorporating a water-soluble dye in the gelatine solution. The solution is then coated on moulds and dried. Hard gelatine capsules are used to hold dry powders. They dissolve in water and immediately release the contents. They are capable of holding oil drugs but they must be sealed to do so.

Soft capsules are useful for liquids and for materials with a distinct odour. They are made of gelatine, but additional materials are added to make them elastic. They cannot be made extemporaneously, and must be sealed after filling.

Tags: Europe
Previous Post

Quintiles Drug Research Unit

Next Post

Vivalis R&D Facility

Related Posts

Pharmapack 2023 a pivotal moment for sustainability in drug delivery and packaging
Europe

Pharmapack 2023 a pivotal moment for sustainability in drug delivery and packaging

3rd March 2023
Dr Reddy's Lab gets DCGI nod for Sputnik Phase 2 & 3 trials
Europe

RDIF and Minapharm Agree to Produce over 40 Million Doses of the Sputnik V Vaccine in Egypt

26th April 2021
Sputnik V: World's First COVID-19 Vaccine Now Available to Public in Russia
Europe

Sputnik V: World’s First COVID-19 Vaccine Now Available to Public in Russia

26th September 2020
AstraZeneca agrees to supply Europe with 400 million doses of COVID-19 vaccine
Europe

Valneva Announces Major COVID-19 Vaccine Partnership with U.K. Government

21st September 2020
Europe

Pharmintech 2019: Big increase in International Participation Expected

18th November 2018
Europe

Novo Nordisk acquires Ziylo Ltd to accelerate its development of glucose responsive insulins

17th August 2018
Next Post

Vivalis R&D Facility

Latest News

Drug Development

New Delivery Path Brings To Light Efficacy of Immunotherapy

1st April 2023
Cathay Cargo signs global airline partnership with Tower Cold Chain
Packaging & Logistic

Cathay Cargo signs global airline partnership with Tower Cold Chain

31st March 2023
Quotient Sciences completes integration of drug substance into Translational Pharmaceutics Platform
Facilities & Operation

£277m Funding Set To Benefit UK Life Sciences Manufacturing

31st March 2023
Drug Development

Nasal Spray Shows Its Effect Against New COVID Variants

27th March 2023
FDA Approvals

Mid-Point Regulatory Science Strategy Study Published By EMA

27th March 2023
Pharma Advancement

About Us

Pharma Advancement is a leading Pharma information centric website. On one side Pharmaadvancement.com has established itself as one of the most efficient and comprehensive source of Pharma information online, dedicated to providing decision makers in all the Pharma industry sectors with reliable, accurate and useful insights into happenings in the Pharma sector.

Qucik Links

  • Drug Development
  • Manufacturing
  • News
  • Events & Conferences
  • Newsletter Archive

Resources

  • Advertise with us
  • Contact Us
  • Download Mediapack

System

  • Search
  • Sitemap
  • RSS Feed

© 2017 Copyright © Valuemediaservices 2017 All rights reserved.

No Result
View All Result
  • Home
  • Drug Development
  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us

© 2017 Copyright © Valuemediaservices 2017 All rights reserved.

Login to your account below

Forgotten Password?

Fill the forms bellow to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In