Thermo Fisher Scientific has unveiled the Applied Biosystems MagMAX HMW DNA Kit, a new solution that supports both manual and automated workflows to enable extraction of High Molecular Weight (HMW) DNA, tailored for use in long-read DNA sequencing.
Developed for efficiency and consistency, the kit makes it easier to isolate large, intact, high-integrity DNA fragments from a wide range of sample types. With this, the laboratories can achieve dependable results while keeping processing time to a minimum.
As genomic applications continue to grow in sectors like biotech, pharmaceuticals, clinical research, and academic fields, the need for more efficient methods suited to long-read DNA sequencing has become evident. Until recently, scientists often had to rely on separate extraction kits depending on their sample type and process, which led to inconsistent results and delayed timelines due to the demands of manual preparation.
The MagMAX HMW DNA Kit responds to this challenge by offering a consistent method for obtaining high-quality HMW DNA. It produces fragments larger than 100 kilobases in under two hours and typically requires only 20 to 30 minutes of hands-on time. Being compatible with Thermo Scientific KingFisher Duo Prime, Flex, and Apex platforms, it allows labs to scale workflow easily while maintaining reproducibility. Its flexible design also includes a range of protocols, enabling labs to scale their operations as project demands shift.
“Researchers working with long-read sequencing face diverse sample types and throughput requirements but share the need for reliable, efficient DNA isolation. Our MagMAX HMW DNA Kit provides a streamlined, automated option that reduces bottlenecks and enables researchers to focus more on discovery,” said Kevin Lowitz, vice president and general manager, sample preparation at Thermo Fisher.
“Our lab relies on long-read sequencing to study genomic structures and variations linked to human disease. The MagMAX HMW DNA Kit offers a simple, scalable solution that consistently produces high molecular weight DNA, ensuring we have trustworthy data for our research.,” said Alexis Tapanes-Castillo, PhD, associate professor of Biology, Lab Director, St. Thomas University.
Designed for speed and precision, the MagMAX HMW DNA Kit provides researchers with high-integrity DNA in less time, helping drive faster breakthroughs in oncology and genomics
