X
Pharma Advancement
  • Home
  • Drug Development
    • All
    • Clinical Trials
    • FDA Approvals
    • Research & Development
    Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer's disease

    Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease

    Fasenra shows consistent safety and sustained efficacy in long-term Phase III BORA trial in severe eosinophilic asthma

    AstraZeneca and IDT Biologika sign LOI to increase COVID-19 vaccine manufacturing in Europe and secure long-term supply capacity

    Astrazeneca Says Covid-19 Long-Acting Antibody Combination AZD7442 Rapidly Advances Into Phase III Clinical Trials

    Algernon Pharmaceuticals Considers Adding Lung Scarring as an Additional Endpoint for its Phase 2b/3 COVID-19 Study Protocol

    Samsung Biologics, National OncoVenture, and Eutilex obtains IND Approval from FDA

    Samsung Biologics, National OncoVenture, and Eutilex obtains IND Approval from FDA

    Vaxart Announces Positive Preliminary Data from Phase 1 Clinical Trial Evaluating Its Oral COVID-19 Tablet Vaccine Candidate

    Vaxart Announces Positive Preliminary Data from Phase 1 Clinical Trial Evaluating Its Oral COVID-19 Tablet Vaccine Candidate

    Gavi, the Vaccine Alliance, Collaborates with Salesforce to Help Equitably Distribute Two Billion COVID-19 Vaccines by the End of 2021

    GSK and CureVac to develop next generation mRNA COVID-19 vaccines

    Oxford leads first trial investigating dosing with alternating vaccines

    Oxford leads first trial investigating dosing with alternating vaccines

    Moderna Provides Business Update and Announces Three New Development Programs in Infectious Disease Vaccines

    Moderna Provides Business Update and Announces Three New Development Programs in Infectious Disease Vaccines

    Merck, Pfizer get EU nod for Bavencio as bladder cancer maintenance

    Merck, Pfizer get EU nod for Bavencio as bladder cancer maintenance

  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us
No Result
View All Result
  • Home
  • Drug Development
    • All
    • Clinical Trials
    • FDA Approvals
    • Research & Development
    Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer's disease

    Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease

    Fasenra shows consistent safety and sustained efficacy in long-term Phase III BORA trial in severe eosinophilic asthma

    AstraZeneca and IDT Biologika sign LOI to increase COVID-19 vaccine manufacturing in Europe and secure long-term supply capacity

    Astrazeneca Says Covid-19 Long-Acting Antibody Combination AZD7442 Rapidly Advances Into Phase III Clinical Trials

    Algernon Pharmaceuticals Considers Adding Lung Scarring as an Additional Endpoint for its Phase 2b/3 COVID-19 Study Protocol

    Samsung Biologics, National OncoVenture, and Eutilex obtains IND Approval from FDA

    Samsung Biologics, National OncoVenture, and Eutilex obtains IND Approval from FDA

    Vaxart Announces Positive Preliminary Data from Phase 1 Clinical Trial Evaluating Its Oral COVID-19 Tablet Vaccine Candidate

    Vaxart Announces Positive Preliminary Data from Phase 1 Clinical Trial Evaluating Its Oral COVID-19 Tablet Vaccine Candidate

    Gavi, the Vaccine Alliance, Collaborates with Salesforce to Help Equitably Distribute Two Billion COVID-19 Vaccines by the End of 2021

    GSK and CureVac to develop next generation mRNA COVID-19 vaccines

    Oxford leads first trial investigating dosing with alternating vaccines

    Oxford leads first trial investigating dosing with alternating vaccines

    Moderna Provides Business Update and Announces Three New Development Programs in Infectious Disease Vaccines

    Moderna Provides Business Update and Announces Three New Development Programs in Infectious Disease Vaccines

    Merck, Pfizer get EU nod for Bavencio as bladder cancer maintenance

    Merck, Pfizer get EU nod for Bavencio as bladder cancer maintenance

  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us
No Result
View All Result
Pharma Advancement
No Result
View All Result
Home News

MaxiVAX and Minaris Regenerative Medicine Enter into a Manufacturing Partnership for MVX-ONCO-2 Cancer Immunotherapy

Content Team by Content Team
22nd February 2021
in News
MaxiVAX and Minaris Regenerative Medicine Enter into a Manufacturing Partnership for MVX-ONCO-2 Cancer Immunotherapy

MaxiVAX SA, a private Swiss clinical-stage biotech company developing novel anti-cancer vaccines, and Minaris Regenerative Medicine GmbH, a leading contract development and manufacturing service provider for the cell and gene therapy industry, have entered into a manufacturing agreement for MVX-ONCO-2, a cell-based immunotherapy for the treatment of cancers such as chordoma, head and neck, and other solid tumors.

The MVX-ONCO-2 consists of two components: 1) biocompatible capsules, loaded with a genetically modified cell-line that secretes a strong immune-booster GM-CSF (granulocyte-macrophage stimulating factor) and 2) irradiated autologous patients’ tumor cells, isolated from patients which serve as tumor antigens. To induce an efficient anti-tumor response against the patients’ own tumor cells, the encapsulated GM-CSF secreting cells are implanted subcutaneously at the site of tumor-cell vaccination.

Minaris will be responsible for the GMP manufacturing, freezing and shipping of the MVX-ONCO-2 capsules, which will be delivered to clinical sites. The autologous patients’ tumor cells will be processed at the clinical sites.

The scope of the manufacturing agreement includes process development for scale-up and technology transfer with the goal of supplying Phase 2 and 3 clinical studies initially in the EU and eventually in the United States. Services will be performed at Minaris’ European site in Ottobrunn near Munich, Germany.

“We are excited to support MaxiVAX with their innovative product,” said Dusan Kosijer, CEO of the European operations of Minaris. “Their unique approach on cancer immunotherapies addresses a significant unmet medical need for patients with difficult-to-treat tumors.”

“We are confident that our partnership with Minaris will accelerate MaxiVAX’s breakthrough cancer immunotherapy development from clinical trial to market success,” said Ksenija Pavletic, an executive board member of MaxiVAX. “Minaris has the expertise and industry experience to enable the delivery of MaxiVAX’s innovative lead product MVX-ONCO-2 to the patients stringently and reliably.”

“Our mission is to develop life changing therapies. It can only be achieved if we manage to effectively deliver such therapies to our patients. In Minaris, we have found a partner that will not only help us in this aspect, but also in developing integrated manufacturing solutions and provide the appropriate infrastructure to support our future commercial production both in the US and in Europe,” added Julien Grogg, VP Technology of MaxiVAX.

The transfer of manufacturing process to an experienced CMO to generate commercial grade MVX-ONCO-2, also fulfills the first milestone obligation of MaxiVAX’s European Commission H2020 funded project – “MaxONCO”. In January 2020, MaxiVAX initiated a two- and half-year project under the SME Instrument Phase 2 H2020 Programme, for which MaxiVAX was awarded € 2,785,300. The SME Instrument supports high-potential small and medium-sized enterprises to help them develop and bring onto the market new innovative products, services and business models that could drive economic growth.

About Minaris Regenerative Medicine
Minaris Regenerative Medicine is a global contract development and manufacturing organization (CDMO) for cell and gene therapies. We offer our clients high value clinical and commercial manufacturing services, development solutions, and technologies. We are pioneers in the field with more than 20 years’ experience providing outstanding quality and reliability. Our facilities in the US, Europe, and Asia allow us to supply patients worldwide with life-changing therapies. Minaris Regenerative Medicine is wholly owned by Showa Denko Materials Co., Ltd.

About MaxiVAX
MaxiVAX is a Phase II clinical-stage biotechnology company advancing patient-specific immunomodulatory strategies for the treatment of cancers. The company has safely treated over 30 patients in Phase I clinical trial and initiated a 40-patient Phase II clinical trial in head and neck cancers in several clinical sites in Switzerland. The company successfully filed an IND with the US FDA in 2018 for chordoma Phase II trials in the US and EU.

Previous Post

Thermo Fisher Scientific: New, online 2D-LC System empowers scientists to confidently characterize complex samples

Related Posts

online 2D-LC System empowers
News

Thermo Fisher Scientific: New, online 2D-LC System empowers scientists to confidently characterize complex samples

22nd February 2021
The Falling Graph of Dose Contract Manufacturing
News

GSK to sell Cephalosporin antibiotics business to Sandoz

22nd February 2021
Johnson & Johnson Prepares to Resume Phase 3 ENSEMBLE Trial of its Janssen COVID-19 Vaccine Candidate in the U.S.
Manufacturing

Evonik strengthens strategic partnership with BioNTech on COVID-19 vaccine

14th February 2021
Qatar approves emergency use of Modernas COVID-19 vaccine
News

Qatar approves emergency use of Modernas COVID-19 vaccine

14th February 2021
Sepha launches small batch Contract Packaging Service
News

Sepha launches small batch Contract Packaging Service

14th February 2021
Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer's disease
Drug Development

Exscientia and the University of Oxford announce partnership to develop treatments for Alzheimer’s disease

14th February 2021

Latest News

MaxiVAX and Minaris Regenerative Medicine Enter into a Manufacturing Partnership for MVX-ONCO-2 Cancer Immunotherapy
News

MaxiVAX and Minaris Regenerative Medicine Enter into a Manufacturing Partnership for MVX-ONCO-2 Cancer Immunotherapy

22nd February 2021
online 2D-LC System empowers
News

Thermo Fisher Scientific: New, online 2D-LC System empowers scientists to confidently characterize complex samples

22nd February 2021
The Falling Graph of Dose Contract Manufacturing
News

GSK to sell Cephalosporin antibiotics business to Sandoz

22nd February 2021
Johnson & Johnson Prepares to Resume Phase 3 ENSEMBLE Trial of its Janssen COVID-19 Vaccine Candidate in the U.S.
Manufacturing

Evonik strengthens strategic partnership with BioNTech on COVID-19 vaccine

14th February 2021
Qatar approves emergency use of Modernas COVID-19 vaccine
News

Qatar approves emergency use of Modernas COVID-19 vaccine

14th February 2021
Pharma Advancement

About Us

Pharma Advancement is a leading Pharma information centric website. On one side Pharmaadvancement.com has established itself as one of the most efficient and comprehensive source of Pharma information online, dedicated to providing decision makers in all the Pharma industry sectors with reliable, accurate and useful insights into happenings in the Pharma sector.

Qucik Links

  • Drug Development
  • Manufacturing
  • News
  • Events & Conferences
  • Newsletter Archive

Resources

  • Advertise with us
  • Contact Us
  • Download Mediapack

System

  • Search
  • Sitemap
  • RSS Feed

© 2017 Copyright © Valuemediaservices 2017 All rights reserved.

No Result
View All Result
  • Home
  • Drug Development
  • Manufacturing
  • Supply Chain
  • Facilities
  • Health & Nutrition
  • Events
  • Contact Us

© 2017 Copyright © Valuemediaservices 2017 All rights reserved.

Login to your account below

Forgotten Password?

Fill the forms bellow to register

All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In